Why fusion releases energy
Light nuclei can combine into a more tightly bound nucleus. The resulting mass difference appears as energy, described by E = mc^2. In D-T fusion, deuterium and tritium create helium-4, a 3.5 MeV alpha particle, and a 14.1 MeV neutron. The neutron carries most of the reaction energy into the blanket.
The hard part is that positively charged nuclei repel each other. Fusion systems use extreme temperature and confinement to make enough collisions succeed often enough to overcome plasma losses.